Colored Stochastic Petri Nets for Modeling Complex Biological Systems
نویسندگان
چکیده
The stochastic modeling of biological systems is gaining more and more attention when stochastic fluctuations need to be described. On the other hand, the biological systems under investigation become much more complex than before. Traditional modeling methods like stochastic Petri nets do not easily scale and thus become difficult to tackle this situation. This paper aims to present a colored stochastic Petri net approach for systems biology to modeling complex biological systems. Specifically, this paper describes a type of biochemically-interpreted colored stochastic Petri nets and their extensions and analysis techniques for systems biology and illustrates their applications using Ca 2+ release sites that consist of a set of coupled Ca 2+ channels.
منابع مشابه
Colored Petri nets to Model and Simulate Biological Systems
Petri nets have become an effective formalism to model biological systems. However, attempts to simulate biological systems by low-level Petri nets are restricted to relatively small models, and they tend to grow quickly for modeling complex systems, which makes it more difficult to manage and understand the nets. Motivated by this, we propose a colored Petri net-based framework for modeling, s...
متن کاملAccessibility Evaluation in Biometric Hybrid Architecture for Protecting Social Networks Using Colored Petri Nets
In the last few decades, technological progress has been made important information systems that require high security, Use safe and efficient methods for protecting their privacy. It is a major challenge to Protecting vital data and the ability to threaten attackers. And this has made it important and necessary to be sensitive to the authentication and identify of individuals in confidential n...
متن کاملAccessibility Evaluation in Biometric Hybrid Architecture for Protecting Social Networks Using Colored Petri Nets
In the last few decades, technological progress has been made important information systems that require high security, Use safe and efficient methods for protecting their privacy. It is a major challenge to Protecting vital data and the ability to threaten attackers. And this has made it important and necessary to be sensitive to the authentication and identify of individuals in confidential n...
متن کاملModeling and Simulation of Molecular Biology Systems Using Petri Nets: Modeling Goals of Various Approaches
Petri nets are a discrete event simulation approach developed for system representation, in particular for their concurrency and synchronization properties. Various extensions to the original theory of Petri nets have been used for modeling molecular biology systems and metabolic networks. These extensions are stochastic, colored, hybrid and functional. This paper carries out an initial review ...
متن کاملRESTART Simulation of Colored Stochastic Petri Nets
In this paper the combination of stochastic colored Petri nets and the RESTART method is proposed to evaluate performance measures of complex systems that depend on rare events. A prototype implementation is described, which is applied to a logistics example.
متن کامل